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The B12 component of your compounded formulation becomes even more important at this dose because the gastrointestinal effects that impair nutrient absorption are at their strongest

Kannan V, Srimadh Bhagavatham SK, Dandamudi RB et al (2024) Integrated clinical and metabolomic analysis identifies molecular signatures, biomarkers, and therapeutic targets in primary angle closure glaucoma

Homocysteine is an amino acid that, in excess, can damage blood vessels, increasing the risk of cardiovascular problems

Some people have experienced gastrointestinal symptoms, such as nausea, diarrhea, appetite suppression, heartburn, and abdominal discomfort, especially with daily doses 200 mg (109)